Aldrich

PEPPSI-IPr catalyst

669032 -

98%

DOWNLOAD MSDS (PDF)

Synonym: [1,3-Bis(2,6-Diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride

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Properties

Related CategoriesCatalysis and Inorganic Chemistry, Homogeneous Pd Catalysts, Palladium
assay98%
mp230 °C

Description

Frequently Asked Questions

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Packaging

1, 5 g in glass btl

Application

• Catalyst for Kumada-Tamao-Corriu (KTC) reaction (eq. 1)
• Catalyst for Negishi coupling reaction (eq. 2)
• Catalyst for Suzuki coupling reaction (eq. 3)
• Catalyst for Buchwald-Hartwig amination reaction (eq. 4)
PEPPSI<SUP>™</SUP>-IPr catalyst

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Legal Information

PEPPSI is a trademark of Total Synthesis Ltd.

Protocols & Applications

Cross-Coupling, Amination and Heck Transformation using PEPPSI Catalysts

Price and Availability


Documents

Certificate of Analysis

Certificate of Origin

Application Guide for Palladium Catalyzed Cross-Coupling (1MB) (958 KB )
ChemFiles Vol 6 No 3 (1 MB )
Structure Search
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Safety Information

SymbolGHS07  GHS07
Signal wordWarning
Hazard statementsH302-H312-H332
Precautionary statementsP280
Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXn
Risk Statements20/21/22
WGK Germany3
Technical information & documentation associated with this product is available in the Safety & Documentation tab.

Articles

PEPPSI™ Catalyst

Professor Mike Organ, along with Drs. Chris O’Brien and Eric Kantchev, have developed an elegant Pd-NHC catalyst system. The title complex PEPPSI stands for Pyridine-Enhanced Precatalyst Preparation ...
William Sommer
Aldrich ChemFiles 2007, 7.10, 22.
Keywords: Aminations, Buchwald-Hartwig amination, Coupling reactions, Cross couplings, Eliminations, Fischer Indole Synthesis, Ligands, Rearrangements, Reductive eliminations

PEPPSI™ Catalyst

Palladium has played a central role in the expeditious preparation of complex organic molecules, since the discovery and subsequent catalytic use of Pd(PPh3)4 by Malatesta, Angoletta and others.1 In ...
Aldrich ChemFiles 2006, 6.3, 2.
Keywords: Addition reactions, Aminations, Arylations, Building blocks, Catalysis, Chromatography, Coupling reactions, Cross couplings, Eliminations, Fischer Indole Synthesis, Flash chromatography, Grignard Reaction, Heck Reaction, Hiyama Coupling, Ligands, Natural product synthesis, Negishi Coupling, Nuclear magnetic resonance spectroscopy, Oxidative additions, Protocol, Rearrangements, Reductions, Reductive eliminations, Substitutions, Suzuki coupling, Suzuki reactions, Transmetalation

PEPPSI™-IPr

Accelerate your small-molecule synthesis and drug discovery success with our innovative catalyst technologies. PEPPSI™-IPr is distinguished by higher efficiency and superior functional group toleranc...

Aldrich ChemFiles 2006, 6.6, 15.


Keywords: Arylations, Drug discovery, Ligands

Related Content

PEPPSI Catalysts in Chemical Synthesis

PEPPSI™-IPr: An air- and water-stable catalysts for industrially useful intermolecular cross-coupling reactions, aminations, and intramolecular Heck transformations.

References

Organ, M. G.; Abdel-Hadi, M. et al. Chem. Eur. J. 150, 150, (2007)

Organ, M. G.; Avola, S. et al. Chem. Eur. J. 12, 4749, (2006)

Kantchev, E. A. B.; Organ, M. G. et al. Angew. Chem. Int. Ed. Engl. 46, 2768 , (2007)

Organ, M. G.; Abdel-Hadi, M. et al. Chem. Eur. J. 14, 2443, (2008)

Organ, M. G.; Avola, S. et al. Chem. Eur. J. 12, 4749, (2006)

Organ, M. G.; Abdel-Hadi, M. et al. Chem. Eur. J. 13, 150, (2007)

Kantchev, E.A.B; O'Brien, C.J.; Organ, M.G. Angew. Chem. Int. Ed. Engl. 46, 2768, (2007)


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